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"These very interesting findings show that prolonged infusions are not inferior to intermittent infusions and may even confer some benefits in reducing resistance emergence," Roberts said. "We await the outcomes of the BLING-3 study in 7,000 sepsis patients receiving continuous infusion vs intermittent infusion of piperacillin or meropenem to Intermittent PPI therapy is comparable to the current guideline-recommended regimen of intravenous bolus plus a continuous infusion of PPIs in patients with endoscopically treated high-risk bleeding ulcers. Guidelines should be revised to recommend intermittent PPI therapy. 7.6 Administering Intermittent Intravenous Medication (Secondary Medication) and Continuous IV Infusions Intravenous intermittent infusion is an infusion of a volume of fluid/medication over a set period of time at prescribed intervals and then stopped until the next dose is required. Continuous versus Intermittent IV Infusion . Sometimes an IV medication or fluid is given continuously, or all the time.
Continuous versus intermittent infusion of vancomycin in adult patients: A systematic review and meta-analysis. Sachar H, Vaidya K, Laine L. Intermittent vs continuous proton pump inhibitor of PPI followed by a continuous PPI infusion for 72 hours to prevent rebleeding. Continuous infusion versus intermittent bolus furosemide in ADHF: An updated meta‐analysis of randomized control trials. J. Hosp. Med. 2012 March;7(3):270- 275 Risk of overcorrection in rapid intermittent bolus vs slow continuous infusion therapies for symptomatic hyponatremia. November 6, 2020 | Brian Dougherty and Feb 1, 2019 Continuous infusions of vancomycin (CIV) are an attractive alternative to IIV in young infants. Data from adult studies reveal an improved We performed a prospective randomized crossover study comparing intermittent intravenous administration (IA) of furosemide with continuous infusion following Extended vs bolus infusion of broad-spectrum β-lactams for febrile neutropenia: an unblinded, randomized trial.
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July 1, 2020. Kenneth Bender, PharmD, MA. Kenneth Bender, PharmD, MA. Hollow-fiber infection model (HFIM) facilitates comparison of intermittent vs continuous infusion of ß-lactam antibiotic for K. pneumoniae. A comparison of intermittent and extended/continuous infusions of However, continuous infusion showed the tendency to be less nephrotoxic than the intermittent infusion of vancomycin.
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2 METHODS This study was approved by the regional ethics committee (REK‐Sør‐Øst, reference number 2016/98), the Norwegian Medicines Agency (EudraCTnr: 2015‐004397‐14) and registered at clinicaltrials.gov (NCT03043781). Intermittent flushing resulted in a significantly longer duration of cannula patency compared to continuous infusion (geometric mean 47.1 vs. 35.4 h, P=0.041).
The aim of this study was to compare pharmacokinetic characteristics between intermittent infusion and continuous infusion of vancomycin for critically ill patients admitted to intensive care units. Methods. Intermittent therapy was administered for 60 minutes and prescribed as a loading dose of 30 mg/kg and continued with 15 mg/kg q12 h. Home; IMEMR; Search Result; Intermittent vs. continuous vancomycin infusion for gram-positive infections: a systematic review and meta-analysis
intermittent boluses or continuous infusion. This is based on economic reasons as well as ease of use.27,28 The 2008 Surviving Sepsis Campaign recommended that a protocol with a sedation goal should be used to reduce the duration of ventilation and secondly, and that sedation be administered either as intermittent boluses or by a continuous
continuous infusion beta-lactams vs.
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Continuous infusion of intravenous furosemide was associated with increased weight reduction (five studies; n = 516; I 2 = 0%; mean difference 0.70; 95%CI 0.12-1.28 kg; p = 0.02); increased total urine output in 24 h (four studies; n = 390; I 2 = 33%; mean difference 461.5; 95%CI 133.7-789.4 ml; p < 0.01); and reduced brain natriuretic peptide (two studies; n = 390; I 2 = 0%; mean difference 399.5; 95%CI 152.7-646.3 ng.l-1; p < 0.01), compared with the bolus group. Intermittent vs Continuous Antibiotic Infusion Investigated In Vitro. July 1, 2020.
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A more recent paper by Stok and Wieringa adds to this discussion by looking exclusively at the use for durations of antibiotics (Continuous infusion versus intermittent flushing: maintaining peripheral intravenous access in newborn infants). As with the previous study this was an observational cohort in which a shift in practice occurred from Continuous infusion was associated with greater weight loss, increased total urine output in 24 h and BNP reduction when compared with intermittent bolus. We did not observe any differences in plasma creatinine at Day 3 or at discharge, incidence of raised creatinine, incidence of hypokalaemia or total urine output in 72 h in either group. Intermittent Administration of Furosemide vs Continuous Infusion Preceded by a Loading Dose for Congestive Heart Failure Several reports have suggested that continuous intravenous administration of loop diuretics may be superior to intermittent administration. Noninferiority for intermittent vs bolus plus continuous-infusion PPI therapy was also seen for rebleeding at 3 days: RR, 0.73; 1-sided 95% CI upper boundary, 1.02; and upper boundary of the 1-sided 95% CI of the absolute risk difference, 0.17% .
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Dosering young infants after continuous infusion in a wound catheter. J. Krylborn, C. Larsson BA, Gradin M, Lind V, Selander B. [Swedish guidelines for prevention. av P Alfredsson · 2016 — sedation, often as continuous infusions for more than three days. Varje grupp erhöll Metadon intermittent var 6:e timme det första dygnet och därefter var 12:e Arterial Catheter, Consumable, SAI Infusion, RFA-01. Venous Catheter, Consumable, Scientific Commodities Inc. BB518-20 & BB31785-V/2 Tabata, Y., Chang, T. M. Intermittent vascular access for extracorporeal of blood and continuous infusion of fluids in the rat without disturbing the animal.
Methods. Intermittent therapy was administered for 60 minutes and prescribed as a loading dose of 30 mg/kg and continued with 15 mg/kg q12 h. Home; IMEMR; Search Result; Intermittent vs. continuous vancomycin infusion for gram-positive infections: a systematic review and meta-analysis intermittent boluses or continuous infusion. This is based on economic reasons as well as ease of use.27,28 The 2008 Surviving Sepsis Campaign recommended that a protocol with a sedation goal should be used to reduce the duration of ventilation and secondly, and that sedation be administered either as intermittent boluses or by a continuous continuous infusion beta-lactams vs. intermittent infusions.